Abstract
The records of 22 children with the diagnosis of idiopathic immune hemolytic anemia were reviewed. Fifty per cent of the children had a history of an antecedent infection and 32% had underlying immune deficiency or lymphoproliferative diseases. The majority (77%) of the patients had an acute self-limited disease which was frequently associated with a positive complement or nongamma Coombs test. The anemia was usually severe, and a number of the children had reticulocytopenia at the time of diagnosis. These children responded rapidly to transfusions and corticosteroids and generally remained well on follow-up. Immnosuppressive drugs did not prove useful in two patients refractory to prednisone, but splenectomy was apparently beneficial in three of four patients so treated. Mortality rate was 18%, with most of the deaths related to an underlying disease.
Original language | English (US) |
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Pages (from-to) | 780-783 |
Number of pages | 4 |
Journal | The Journal of pediatrics |
Volume | 88 |
Issue number | 5 |
DOIs | |
State | Published - May 1976 |
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health