Technical Refinements with the Use of Biologic Healing Agents

Rami P. Dibbs, Monal Depani, James F. Thornton

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Soft tissue defects resulting from trauma, vascular disease, burns, and postoncologic resections require reconstructive surgery for appropriate wound coverage and support. Dermal substitutes have been applied to a vast array of reconstructive settings across nearly all anatomical areas with demonstrable success. However, they require meticulous handling and operative technical expertise to optimize management of these soft tissue defects. In this review, we will address three dermal substitutes, their operative techniques, and their surgical applications.

Original languageEnglish (US)
Pages (from-to)8-16
Number of pages9
JournalSeminars in Plastic Surgery
Issue number1
StatePublished - Feb 2022
Externally publishedYes


  • ACell
  • AlloDerm
  • Integra
  • biologics
  • dermal substitute

ASJC Scopus subject areas

  • Surgery


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