Tear lysozyme measurements in chronic blepharitis

J. M. Dougherty, J. P. McCulley

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Tear lysozyme concentrations were measured on 47 patients with chronic blepharitis and 22 normal control patients. The patients consisted of 26 individuals with various types of chronic blepharitis alone and 21 individuals with chronic blepharitis and clinically-diagnosed keratoconjunctivitis sicca (KCS). The mean lysozyme concentration of blepharitis patients without KCS (4070 μg/ml) was not significantly different from normals (3760 μg/ml). However, mean lysozyme concentration of the blepharitis patients without KCS (2530 μg/ml) was significantly lower than normals or blepharitis patients with KCS (p < 0.01). It was concluded that tear lysozyme deficiency does not play a significant role in the etiology of chronic blepharitis. However, a large percentage of patients with chronic blepharitis were found to have KCS.

Original languageEnglish (US)
Pages (from-to)53-57
Number of pages5
JournalAnnals of ophthalmology
Issue number1
StatePublished - Jan 1 1985

ASJC Scopus subject areas

  • Ophthalmology


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