Targeting the glucocorticoid receptor in breast and prostate cancers

Jacob Kach, Suzanne D. Conzen, Russell Z. Szmulewitz

Research output: Contribution to journalReview articlepeer-review

53 Scopus citations


Steroid receptors for androgens and estrogens have essential roles in prostate and breast cancers. Recently, glucocorticoid receptor (GR) activity has also been proposed as having an important role in these cancers. Underscoring the cooperative nature of nuclear receptor activity, data now suggest that GR function in prostate and breast cancers is dependent on the tumor's concomitant androgen or estrogen receptor activity.

Original languageEnglish (US)
Article number7531
JournalScience translational medicine
Issue number305
StatePublished - Sep 16 2015
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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