Abstract
Ubiquitin ligases (E3s) and ubiquitin-specific proteases (USPs) dynamically oppose each other during ubiquitination. In this issue of Molecular Cell, Huang et al. (2011) provide a counterintuitive example of a USP residing in an E3 complex, and establish Usp37 as a gatekeeper of APC/C-mediated ubiquitination of cyclin A.
Original language | English (US) |
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Pages (from-to) | 409-410 |
Number of pages | 2 |
Journal | Molecular cell |
Volume | 42 |
Issue number | 4 |
DOIs | |
State | Published - May 20 2011 |
ASJC Scopus subject areas
- Molecular Biology
- Cell Biology