Synthetic Studies toward the Myrioneuron Alkaloids

Jake M. Aquilina, Myles W. Smith

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

The Myrioneuron alkaloids are a relatively small family of plant-derived alkaloids that present an intriguing array of structural intricacy and biological properties. As such, these natural products have drawn interest from the synthetic community, resulting in creative total syntheses of several family members. This review showcases recent synthetic efforts towards these polycyclic alkaloids. 1 Introduction 1.1 Biological Activity 1.2 Proposed Biosynthesis 2 Synthetic Studies toward the Myrioneuron Alkaloids 2.1 Total Synthesis of Myrioxazines A and B 2.2 Total Synthesis of Myrionine, Myrionidine, and Schoberine 2.3 Total Synthesis of Myrifabrals A and B 2.4 Total Synthesis of Myrioneurinol 3 Conclusions and Outlook.

Original languageEnglish (US)
Pages (from-to)3725-3736
Number of pages12
JournalSynthesis (Germany)
Volume55
Issue number22
DOIs
StatePublished - Mar 24 2023

Keywords

  • Myrioneuron
  • alkaloids
  • asymmetric synthesis
  • biosynthesis
  • total synthesis

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

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