Synthesis of the Hypoxia-Inducible Factor-2α (HIF-2α) Inhibitor, 3-[(1S,2S,3R)-2,3-Difluoro-1-hydroxy-7-methylsulfonylindan-4-yl]oxy-5-fluorobenzonitrile (PT2977, Belzutifan); Efficient Replication of Established Approaches

Khagendra B. Hamal, Cyprian I. Pavlich, Graham J. Carlson, Yu Ching Wong, Fangzhou Zhao, Qing Zhang, Kevin K. Klausmeyer, Kevin G. Pinney

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