Synthesis of oligonucleotide-peptide and oligonucleotide-protein conjugates.

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


The conjugation of macromolecules offers a rapid and versatile route to improved function. Here, the methods for obtaining disulfide-linked oligonucleotide-peptide and oligonucleotide-protein conjugates are described. These hybrid molecules can be used deliver chemical functionality to specific sequences within deoxyribonucleic acid and ribonucleic acid. The peptides and proteins can also be used to enhance the hybridization properties of the attached oligonucleotides.

Original languageEnglish (US)
Pages (from-to)197-206
Number of pages10
JournalMethods in molecular biology (Clifton, N.J.)
StatePublished - 2004

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics


Dive into the research topics of 'Synthesis of oligonucleotide-peptide and oligonucleotide-protein conjugates.'. Together they form a unique fingerprint.

Cite this