Abstract
(Chemical Equation Presented) Exploiting an opening: Lewis acid promoted ring-opening of donor-acceptor cyclopropanes generates a 1,3-zwitterion; cycloaddition with a silyl ynol ether leads to a general synthesis of cyclopentenones (see scheme). Substitution is tolerated on the ynol and on all positions of the cyclopropane to give tri-, tetra-, and penta-substituted cyclopentenones in high yield.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 7068-7070 |
| Number of pages | 3 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 47 |
| Issue number | 37 |
| DOIs | |
| State | Published - Sep 1 2008 |
Keywords
- Cycloaddition
- Cyclopentenones
- Xyclopropanes
- Ynols
ASJC Scopus subject areas
- Catalysis
- General Chemistry