Synthesis and antimicrobial activity of new substituted 10‐methyl‐1,2‐dihydro‐1‐oxo‐1,2,4‐triazino(4,5‐a)indoles

S. B. Rajur, A. Y. Merwade, L. D. Basanagoudar, P. V. Kulkarni

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Ten new 4,8‐disubstituted 10‐methyl‐1,2‐dihydro‐1‐oxo‐1,2,4‐triazino(4,5‐a)indoles (5 and 6) were prepared by refluxing various 5‐substituted indole‐2‐carbohydrazides (4) with triethylorthoformate or triethylorthoacetate in dimethylformamide. These derivatives were evaluated for their antimicrobial activity. Some of the title compounds possess fairly potent antimicrobial activity.

Original languageEnglish (US)
Pages (from-to)780-782
Number of pages3
JournalJournal of Pharmaceutical Sciences
Issue number9
StatePublished - Sep 1989

ASJC Scopus subject areas

  • Pharmaceutical Science


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