Susceptibility to lupus nephritis in the NZB/W model system

Laurence Morel; Edward K. Wakeland

doi:10.1016/S0952-7915(98)80094-0

Susceptibility to lupus nephritis in the NZB/W model system

Laurence Morel, Edward K. Wakeland

Research output: Contribution to journal › Article › peer-review

62 Scopus citations

Abstract

Advances in genetic mapping have resulted in the identification of multiple lupus susceptibility loci in the NZB/W mouse model. The analysis of congenic strains carrying these loci is now providing functional data on their role in lupus pathogenesis and is paving the way to the identification of the susceptibility genes and their molecular characterization.

Original language	English (US)
Pages (from-to)	718-725
Number of pages	8
Journal	Current Opinion in Immunology
Volume	10
Issue number	6
DOIs	https://doi.org/10.1016/S0952-7915(98)80094-0
State	Published - Dec 1998

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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title = "Susceptibility to lupus nephritis in the NZB/W model system",

abstract = "Advances in genetic mapping have resulted in the identification of multiple lupus susceptibility loci in the NZB/W mouse model. The analysis of congenic strains carrying these loci is now providing functional data on their role in lupus pathogenesis and is paving the way to the identification of the susceptibility genes and their molecular characterization.",

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year = "1998",

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AU - Wakeland, Edward K.

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AB - Advances in genetic mapping have resulted in the identification of multiple lupus susceptibility loci in the NZB/W mouse model. The analysis of congenic strains carrying these loci is now providing functional data on their role in lupus pathogenesis and is paving the way to the identification of the susceptibility genes and their molecular characterization.

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Susceptibility to lupus nephritis in the NZB/W model system

Abstract

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