Abstract
Barrett’s esophagus (BE) surveillance remains fraught with controversy and variation in real-world clinical practices. The application of current guideline-recommended surveillance intervals has not significantly impacted the incidence of esophageal adenocarcinoma (EAC), nor survival. One fifth of patients with EAC present in the first year after a negative upper endoscopy. Additionally, the progression from BE to EAC may occur in a non-linear fashion and more rapidly than previously believed due sudden genomic catastrophes requiring intensified surveillance. Emerging data supports the role of molecular markers for risk stratification and a more patient-centered surveillance approach rather than less vigorous universal surveillance intervals.
Original language | English (US) |
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Pages (from-to) | 75-79 |
Number of pages | 5 |
Journal | Foregut |
Volume | 3 |
Issue number | 1 |
DOIs | |
State | Published - Mar 2023 |
Keywords
- Barrett’s esophagus
- esophageal adenocarcinoma
- short interval
- surveillance
ASJC Scopus subject areas
- Gastroenterology
- Surgery
- Oncology