68Ga-PSMA-Avid Liver Metastases From Colon Cancer, Not Visualized on FDG PET Scan

Abtin Doroudinia; Satyanarayana Chekuri

doi:10.1097/RLU.0000000000004850

⁶⁸Ga-PSMA-Avid Liver Metastases From Colon Cancer, Not Visualized on FDG PET Scan

Abtin Doroudinia, Satyanarayana Chekuri

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

¹⁸F-FDG PET/CT scan is a well-known modality to assess distant metastases and treatment response in the patients with primary colon cancer. We are presenting an interesting case of ⁶⁸Ga-PSMA-avid liver metastases in a 74-year-old man with colon cancer and recently diagnosed prostate cancer. The liver metastases were positive on initial FDG PET but lost FDG avidity on subsequent posttreatment FDG PET scans. Biopsy from the PSMA-avid liver lesions confirmed metastasis from colon origin. PSMA is expressed in various forms of tumor neovasculature other than prostate cancer with potential new applications as a theranostic agent in the future.

Original language	English (US)
Pages (from-to)	E547-E548
Journal	Clinical nuclear medicine
Volume	48
Issue number	11
DOIs	https://doi.org/10.1097/RLU.0000000000004850
State	Published - Nov 1 2023
Externally published	Yes

Keywords

PSMA avid
colon cancer
liver metastasis

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

Access to Document

10.1097/RLU.0000000000004850

Cite this

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title = "68Ga-PSMA-Avid Liver Metastases From Colon Cancer, Not Visualized on FDG PET Scan",

abstract = "18F-FDG PET/CT scan is a well-known modality to assess distant metastases and treatment response in the patients with primary colon cancer. We are presenting an interesting case of 68Ga-PSMA-avid liver metastases in a 74-year-old man with colon cancer and recently diagnosed prostate cancer. The liver metastases were positive on initial FDG PET but lost FDG avidity on subsequent posttreatment FDG PET scans. Biopsy from the PSMA-avid liver lesions confirmed metastasis from colon origin. PSMA is expressed in various forms of tumor neovasculature other than prostate cancer with potential new applications as a theranostic agent in the future.",

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AB - 18F-FDG PET/CT scan is a well-known modality to assess distant metastases and treatment response in the patients with primary colon cancer. We are presenting an interesting case of 68Ga-PSMA-avid liver metastases in a 74-year-old man with colon cancer and recently diagnosed prostate cancer. The liver metastases were positive on initial FDG PET but lost FDG avidity on subsequent posttreatment FDG PET scans. Biopsy from the PSMA-avid liver lesions confirmed metastasis from colon origin. PSMA is expressed in various forms of tumor neovasculature other than prostate cancer with potential new applications as a theranostic agent in the future.

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