Successful large volume leukapheresis on a small infant allogeneic donor

J. Pahys, V. Fisher, M. Carneval, R. Yomtovian, R. Sarode, M. Nieder

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


We successfully performed a hematopoietic stem cell apheresis on the smallest allogeneic donor reported to date, a 6.1 kg female. After placement of a dialysis catheter in the left femoral vein, the COBE Spectra was primed with one unit of paternal whole blood. Heparin and anticoagulant citrate dextrose, solution A (ACD-A) were slowly administered to the patient. Ionized calcium levels were checked hourly and calcium gluconate was given for hypocalcemia. Coagulation parameters were checked throughout the procedure. We collected 4.4 x 106 CD34+ cells/kg (recipient). The donor tolerated the procedure well and was discharged the following day. Five months later, the child manifests no obvious late effects.

Original languageEnglish (US)
Pages (from-to)339-341
Number of pages3
JournalBone Marrow Transplantation
Issue number3
StatePublished - 2000


  • Allogeneic donor
  • Infant
  • Leukapheresis

ASJC Scopus subject areas

  • Hematology
  • Transplantation


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