Structure of a family of rat amylase genes

Raymond J. MacDonald; Michael M. Crerar; William F. Swain; Raymond L. Pictet; Gilles Thomas; William J. Rutter

doi:10.1038/287117a0

Structure of a family of rat amylase genes

Raymond J. MacDonald, Michael M. Crerar, William F. Swain, Raymond L. Pictet, Gilles Thomas, William J. Rutter

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Abstract

The sequences of two cloned rat pancreatic amylase cDNAs comprising 95% of the mRNA sequence are reported. Analysis of cloned rat genomic DNA fragments using cloned cDNA probes indicates that the rat genome contains multiple closely related amylase genes in which the cDNA sequences are distributed within a region 9 kilobases in length and are interrupted by at least seven intervening sequences.

Original language	English (US)
Pages (from-to)	117-122
Number of pages	6
Journal	Nature
Volume	287
Issue number	5778
DOIs	https://doi.org/10.1038/287117a0
State	Published - 1980

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@article{5239bfa5139c4c1f9b3a0dae8ba8deb1,

title = "Structure of a family of rat amylase genes",

abstract = "The sequences of two cloned rat pancreatic amylase cDNAs comprising 95% of the mRNA sequence are reported. Analysis of cloned rat genomic DNA fragments using cloned cDNA probes indicates that the rat genome contains multiple closely related amylase genes in which the cDNA sequences are distributed within a region 9 kilobases in length and are interrupted by at least seven intervening sequences.",

author = "MacDonald, {Raymond J.} and Crerar, {Michael M.} and Swain, {William F.} and Pictet, {Raymond L.} and Gilles Thomas and Rutter, {William J.}",

year = "1980",

doi = "10.1038/287117a0",

language = "English (US)",

volume = "287",

pages = "117--122",

journal = "Nature",

issn = "0028-0836",

publisher = "Nature Publishing Group",

number = "5778",

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TY - JOUR

T1 - Structure of a family of rat amylase genes

AU - MacDonald, Raymond J.

AU - Crerar, Michael M.

AU - Swain, William F.

AU - Pictet, Raymond L.

AU - Thomas, Gilles

AU - Rutter, William J.

PY - 1980

Y1 - 1980

N2 - The sequences of two cloned rat pancreatic amylase cDNAs comprising 95% of the mRNA sequence are reported. Analysis of cloned rat genomic DNA fragments using cloned cDNA probes indicates that the rat genome contains multiple closely related amylase genes in which the cDNA sequences are distributed within a region 9 kilobases in length and are interrupted by at least seven intervening sequences.

AB - The sequences of two cloned rat pancreatic amylase cDNAs comprising 95% of the mRNA sequence are reported. Analysis of cloned rat genomic DNA fragments using cloned cDNA probes indicates that the rat genome contains multiple closely related amylase genes in which the cDNA sequences are distributed within a region 9 kilobases in length and are interrupted by at least seven intervening sequences.

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U2 - 10.1038/287117a0

DO - 10.1038/287117a0

M3 - Article

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AN - SCOPUS:0019123050

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VL - 287

SP - 117

EP - 122

JO - Nature

JF - Nature

IS - 5778

ER -

Structure of a family of rat amylase genes

Abstract

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