Striking a balance: Inter-kingdom cell-to-cell signaling, friendship or war?

Vanessa Sperandio

Research output: Contribution to journalShort surveypeer-review

8 Scopus citations


There is a growing body of evidence suggesting that bacterial signaling molecules are involved in cross-kingdom communication with eukaryotic cells. Bacterial signaling molecules can enter eukaryotic cells and appear to modulate immune responses to bacterial pathogens. Recently, an enticing study demonstrated that mammalian airway epithelial cells have the ability to inactivate these bacterial signaling molecules, suggesting that this activity might have a role in the host innate response against bacterial infections.

Original languageEnglish (US)
Pages (from-to)505-507
Number of pages3
JournalTrends in Immunology
Issue number10
StatePublished - Oct 2004

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


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