STING for vesicoureteral reflux

Selcuk Yucel, Linda A. Baker

Research output: Chapter in Book/Report/Conference proceedingChapter


Vesicouretal reflux (VUR) is the retrograde flow of urine from the bladder into the upper urinary system. It affects 1% of boys and girls. The ureterovesical junction is compromised by short submucosal ureteral length, insufficient detrusor backing to the ureter, and/or periureteral diverticuli. Vesicoureteral reflux is present in 29% to 70% of children with urinary infections1,2 and is typically diagnosed by contrast voiding cystourethrogram or nuclear cystogram. The association among VUR, urinary tract infections (UTIs), and renal scarring has been noted for years. The overall goal of managing the child with UTIs is to prevent renal scarring, hypertension, or chronic renal failure. In fact, 3% to 25% of children with end-stage renal disease lost their renal function because of reflux nephropathy.2,3 Renal scarring is detected best by DMSA scanning. However, some of the radiologically detected changes are congenital in nature and not acquired from postnatal UTIs (males > females).4,5

Original languageEnglish (US)
Title of host publicationPediatric Endourology Techniques
PublisherSpringer London
Number of pages8
ISBN (Print)1846283868, 9781846283864
StatePublished - 2007

ASJC Scopus subject areas

  • General Medicine


Dive into the research topics of 'STING for vesicoureteral reflux'. Together they form a unique fingerprint.

Cite this