Stereospecific synthesis of trans-arachidonic acids

U. Murali Krishna, M. Muralidhar Reddy, Jianing Xia, J. R. Falck, Michael Balazy

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


An effective synthesis is described for the preparation of all four mono trans isomers of arachidonic acid via deoxidation of epoxide precursors with lithium diphenylphosphide and quaternization with methyl iodide.

Original languageEnglish (US)
Pages (from-to)2415-2418
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Issue number18
StatePublished - Sep 17 2001

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry


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