TY - JOUR
T1 - Stem Cells
T2 - A Renaissance in Human Biology Research
AU - Wu, Jun
AU - Izpisua Belmonte, Juan Carlos
N1 - Publisher Copyright:
© 2016 Elsevier Inc.
PY - 2016/6/16
Y1 - 2016/6/16
N2 - The understanding of human biology and how it relates to that of other species represents an ancient quest. Limited access to human material, particularly during early development, has restricted researchers to only scratching the surface of this inherently challenging subject. Recent technological innovations, such as single cell "omics" and human stem cell derivation, have now greatly accelerated our ability to gain insights into uniquely human biology. The opportunities afforded to delve molecularly into scarce material and to model human embryogenesis and pathophysiological processes are leading to new insights of human development and are changing our understanding of disease and choice of therapy options.
AB - The understanding of human biology and how it relates to that of other species represents an ancient quest. Limited access to human material, particularly during early development, has restricted researchers to only scratching the surface of this inherently challenging subject. Recent technological innovations, such as single cell "omics" and human stem cell derivation, have now greatly accelerated our ability to gain insights into uniquely human biology. The opportunities afforded to delve molecularly into scarce material and to model human embryogenesis and pathophysiological processes are leading to new insights of human development and are changing our understanding of disease and choice of therapy options.
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U2 - 10.1016/j.cell.2016.05.043
DO - 10.1016/j.cell.2016.05.043
M3 - Review article
C2 - 27315475
AN - SCOPUS:84975282927
SN - 0092-8674
VL - 165
SP - 1572
EP - 1585
JO - Cell
JF - Cell
IS - 7
ER -