Status of multidrug resistant tuberculosis (MDR-TB) among the Sahariya tribe of North Central India

Ravi Prakash, Dilip Kumar, Vinod K. Gupta, Sanjay Jain, Devendra S. Chauhan, Pramod K. Tiwari, Vishwa M. Katoch

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Background: The incidence/prevalence of tuberculosis (TB) is reported to be high in the Sahariya tribe of North Central India. The outbreaks of different drug-resistant isolates of Mycobacterium tuberculosis emphasized the need for continuous monitoring of resistance to anti-tuberculosis drugs. This study aimed to assess the profile of multidrug resistant TB among the Sahariya tribe and their non-tribal neighbors for first line drugs through field-based investigations. Methodology: A total of 274 sputum positive pulmonary TB individuals were enrolled and studied for their drug susceptibility profile by the proportion method. Results: A total of 21 cases from Sahariya and 6 from non-tribes were identified with MDR-TB. Thus Sahariya tribe showed a 1.95-fold increased risk of developing drug resistance than non-tribes. Significant differences were observed for developing drug sensitivity between Sahariya males and females when analyzed for resistance developed to any drug and overall drug resistance vs. sensitive isolates, respectively. A 4.46-fold risk was found for MDR-TB among the smokers of Sahariya tribe, whereas, the non-tribes did not show any significant association. Conclusion: The drug susceptibility profile developed in the present study indicates that drug-resistant tuberculosis is emerging as a serious public health concern in Sahariya tribe. Urgent and effective control measures and better management policies are needed for the prevention of MDR-TB in the tribe.

Original languageEnglish (US)
Pages (from-to)289-297
Number of pages9
JournalJournal of Infection and Public Health
Issue number3
StatePublished - May 1 2016
Externally publishedYes


  • MDR-TB
  • Mycobacterium tuberculosis
  • Sahariya tribe

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases


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