Abstract
'Statins' are 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors - oral cholesterol-lowering drugs that are used to treat hypercholesterolaemia. It is widely accepted that statins have anti-inflammatory effects that are independent of their ability to lower cholesterol. Animal studies and observational clinical studies have indicated that statins might also be effective in treating certain neurological diseases - in particular, multiple sclerosis, Alzheimer's disease and ischaemic stroke. At present, however, results from ongoing prospective, randomized clinical trials are not available.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 325-331 |
| Number of pages | 7 |
| Journal | Nature Reviews Neuroscience |
| Volume | 6 |
| Issue number | 4 |
| DOIs | |
| State | Published - Apr 2005 |
ASJC Scopus subject areas
- General Neuroscience