Spontaneous medication-related osteonecrosis of the jaws in a 23-year-Old

Brenden J. Manley; Timothy W. Neal; Shyam Indrakanti; Thomas Schlieve

doi:10.1016/j.omsc.2022.100289

Spontaneous medication-related osteonecrosis of the jaws in a 23-year-Old

Brenden J. Manley, Timothy W. Neal, Shyam Indrakanti, Thomas Schlieve

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Medication-related osteonecrosis is a well-documented yet rare complication of antiresorptive treatment. The risk of MRONJ is well established in the adult population but has yet to be established in the pediatric population. Additionally, the risk to this population in adulthood following many years of antiresorptive use is unknown. This case report describes a patient who received long-term antiresorptive medication as an adolescent and spontaneously developed MRONJ at age 23. To the authors’ knowledge, this is the youngest patient with MRONJ reported in the literature.

Original language	English (US)
Article number	100289
Journal	Oral and Maxillofacial Surgery Cases
Volume	9
Issue number	1
DOIs	https://doi.org/10.1016/j.omsc.2022.100289
State	Published - Mar 2023
Externally published	Yes

Keywords

Antiresorptive
Bisphosphonate
Osteonecrosis

ASJC Scopus subject areas

Surgery
Oral Surgery
Otorhinolaryngology

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10.1016/j.omsc.2022.100289

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title = "Spontaneous medication-related osteonecrosis of the jaws in a 23-year-Old",

abstract = "Medication-related osteonecrosis is a well-documented yet rare complication of antiresorptive treatment. The risk of MRONJ is well established in the adult population but has yet to be established in the pediatric population. Additionally, the risk to this population in adulthood following many years of antiresorptive use is unknown. This case report describes a patient who received long-term antiresorptive medication as an adolescent and spontaneously developed MRONJ at age 23. To the authors{\textquoteright} knowledge, this is the youngest patient with MRONJ reported in the literature.",

keywords = "Antiresorptive, Bisphosphonate, Osteonecrosis",

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AU - Manley, Brenden J.

AU - Neal, Timothy W.

AU - Indrakanti, Shyam

AU - Schlieve, Thomas

PY - 2023/3

Y1 - 2023/3

N2 - Medication-related osteonecrosis is a well-documented yet rare complication of antiresorptive treatment. The risk of MRONJ is well established in the adult population but has yet to be established in the pediatric population. Additionally, the risk to this population in adulthood following many years of antiresorptive use is unknown. This case report describes a patient who received long-term antiresorptive medication as an adolescent and spontaneously developed MRONJ at age 23. To the authors’ knowledge, this is the youngest patient with MRONJ reported in the literature.

AB - Medication-related osteonecrosis is a well-documented yet rare complication of antiresorptive treatment. The risk of MRONJ is well established in the adult population but has yet to be established in the pediatric population. Additionally, the risk to this population in adulthood following many years of antiresorptive use is unknown. This case report describes a patient who received long-term antiresorptive medication as an adolescent and spontaneously developed MRONJ at age 23. To the authors’ knowledge, this is the youngest patient with MRONJ reported in the literature.

KW - Antiresorptive

KW - Bisphosphonate

KW - Osteonecrosis

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Spontaneous medication-related osteonecrosis of the jaws in a 23-year-Old

Abstract

Keywords

ASJC Scopus subject areas

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