Spectral localization of arbitrarily shaped regions of interest (SLASH) using single voxel signals

Zhiyue Wang; Ravinder Reddy; John C. Haselgrove; Cheng Yu Chen; Gadi Goelman; Robert A. Zimmerman; John S. Leigh

doi:10.1016/0730-725X(93)90248-C

Spectral localization of arbitrarily shaped regions of interest (SLASH) using single voxel signals

Zhiyue Wang, Ravinder Reddy, John C. Haselgrove, Cheng Yu Chen, Gadi Goelman, Robert A. Zimmerman, John S. Leigh

Research output: Contribution to journal › Article › peer-review

Abstract

A method for obtaining localized spectra from arbitrarily shaped regions of interest is described. When a sample consists of homogeneous compartments or domains, spectra localized in each compartment can be obtained from signals of single voxels with regular shapes by solving a set of simultaneous linear equations. Experimental demonstrations on a phantom and on human brain in vivo for a two compartment, two voxel case are presented. The issue of signal-to-noise ratio is also discussed.

Original language	English (US)
Pages (from-to)	1203-1208
Number of pages	6
Journal	Magnetic Resonance Imaging
Volume	11
Issue number	8
DOIs	https://doi.org/10.1016/0730-725X(93)90248-C
State	Published - 1993

Keywords

Arbitrary shape
Brain
Localization
Magnetic resonance spectroscopy

ASJC Scopus subject areas

Biophysics
Biomedical Engineering
Radiology Nuclear Medicine and imaging

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10.1016/0730-725X(93)90248-C

Cite this

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title = "Spectral localization of arbitrarily shaped regions of interest (SLASH) using single voxel signals",

abstract = "A method for obtaining localized spectra from arbitrarily shaped regions of interest is described. When a sample consists of homogeneous compartments or domains, spectra localized in each compartment can be obtained from signals of single voxels with regular shapes by solving a set of simultaneous linear equations. Experimental demonstrations on a phantom and on human brain in vivo for a two compartment, two voxel case are presented. The issue of signal-to-noise ratio is also discussed.",

keywords = "Arbitrary shape, Brain, Localization, Magnetic resonance spectroscopy",

author = "Zhiyue Wang and Ravinder Reddy and Haselgrove, {John C.} and Chen, {Cheng Yu} and Gadi Goelman and Zimmerman, {Robert A.} and Leigh, {John S.}",

note = "Funding Information: Acknowledgments-Thisw ork is supportedin part by NIH Grant RR 02305 anrde searchfu nding from SiemensM edicalSystems.",

year = "1993",

doi = "10.1016/0730-725X(93)90248-C",

language = "English (US)",

volume = "11",

pages = "1203--1208",

journal = "Magnetic Resonance Imaging",

issn = "0730-725X",

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TY - JOUR

T1 - Spectral localization of arbitrarily shaped regions of interest (SLASH) using single voxel signals

AU - Wang, Zhiyue

AU - Reddy, Ravinder

AU - Haselgrove, John C.

AU - Chen, Cheng Yu

AU - Goelman, Gadi

AU - Zimmerman, Robert A.

AU - Leigh, John S.

N1 - Funding Information: Acknowledgments-Thisw ork is supportedin part by NIH Grant RR 02305 anrde searchfu nding from SiemensM edicalSystems.

PY - 1993

Y1 - 1993

N2 - A method for obtaining localized spectra from arbitrarily shaped regions of interest is described. When a sample consists of homogeneous compartments or domains, spectra localized in each compartment can be obtained from signals of single voxels with regular shapes by solving a set of simultaneous linear equations. Experimental demonstrations on a phantom and on human brain in vivo for a two compartment, two voxel case are presented. The issue of signal-to-noise ratio is also discussed.

AB - A method for obtaining localized spectra from arbitrarily shaped regions of interest is described. When a sample consists of homogeneous compartments or domains, spectra localized in each compartment can be obtained from signals of single voxels with regular shapes by solving a set of simultaneous linear equations. Experimental demonstrations on a phantom and on human brain in vivo for a two compartment, two voxel case are presented. The issue of signal-to-noise ratio is also discussed.

KW - Arbitrary shape

KW - Brain

KW - Localization

KW - Magnetic resonance spectroscopy

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AN - SCOPUS:0027362502

SN - 0730-725X

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SP - 1203

EP - 1208

JO - Magnetic Resonance Imaging

JF - Magnetic Resonance Imaging

IS - 8

ER -

Spectral localization of arbitrarily shaped regions of interest (SLASH) using single voxel signals

Abstract

Keywords

ASJC Scopus subject areas

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