TY - JOUR
T1 - Software for analyzing the behavioural test "morris Water Maze"
AU - Zorin, Arseny
AU - Chernyuk, Daria
AU - Vlasova, Olga
AU - Bolsunovskaya, Marina
AU - Bezprozvanny, Ilya
N1 - Publisher Copyright:
© The Authors, published by EDP Sciences, 2020.
PY - 2020/11/5
Y1 - 2020/11/5
N2 - The Morris Water Maze Behavioural Test is a universal method for testing cognitive functions in experimental rodents, and it is especially effective in detecting deviations in memory functions and learning, which makes it indispensable in the study of neurodegenerative diseases, effect of therapeutic drugs, rodent stroke and aging models etc. However, despite the wide range of possible applications, data analysis makes the use of this test difficult. Currently, automated tracking and analysis programs of rodent moving are becoming to be popular. Thus, our goal was to develop and create an available quality product, which will allow the scientist to carry out research as efficiently as possible doing various options of the "Morris water maze"using latest modern parameters. In this article, we analyze different types of the Morris water maze methodology and the current scientific parameters of this test to understand the necessary and optimal capabilities of the future program, then to overcome the limitations of the systems currently available we have combined detection and tracking techniques into one standalone tool. The result of the work is a software product that allows to quickly and accurately detect the trajectory of animal moving in the water, and also provides parameters for evaluating the cognitive functions of memory and learning.
AB - The Morris Water Maze Behavioural Test is a universal method for testing cognitive functions in experimental rodents, and it is especially effective in detecting deviations in memory functions and learning, which makes it indispensable in the study of neurodegenerative diseases, effect of therapeutic drugs, rodent stroke and aging models etc. However, despite the wide range of possible applications, data analysis makes the use of this test difficult. Currently, automated tracking and analysis programs of rodent moving are becoming to be popular. Thus, our goal was to develop and create an available quality product, which will allow the scientist to carry out research as efficiently as possible doing various options of the "Morris water maze"using latest modern parameters. In this article, we analyze different types of the Morris water maze methodology and the current scientific parameters of this test to understand the necessary and optimal capabilities of the future program, then to overcome the limitations of the systems currently available we have combined detection and tracking techniques into one standalone tool. The result of the work is a software product that allows to quickly and accurately detect the trajectory of animal moving in the water, and also provides parameters for evaluating the cognitive functions of memory and learning.
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U2 - 10.1051/e3sconf/202020301029
DO - 10.1051/e3sconf/202020301029
M3 - Conference article
AN - SCOPUS:85096594191
SN - 2267-1242
VL - 203
JO - E3S Web of Conferences
JF - E3S Web of Conferences
M1 - 01029
T2 - 2020 Ecological and Biological Well-Being of Flora and Fauna, EBWFF 2020
Y2 - 23 September 2020 through 24 September 2020
ER -