Single-photon tomographic determination of regional cerebral blood flow in epilepsy.

F. J. Bonte, M. D. Devous, E. M. Stokely, R. W. Homan

Research output: Contribution to journalArticlepeer-review

47 Scopus citations


Using a single-photon emission computed tomographic scanner (SPECT) the authors determined regional cerebral blood flow (rCBF) with inhaled xenon-133, a noninvasive procedure. Studies were performed in 40 normal individuals, and these were compared with rCBF determinations in 51 patients with seizure disorders. Although positive results were obtained in 15 of 16 patients with mass lesions, the group of principal interest comprised 25 patients suffering from "temporal lobe" epilepsy. Only one of these had a positive x-ray computed tomogram, but 16 had positive findings on rCBF study. These findings included increased local blood flow in the ictal state and reduced flow interictally.

Original languageEnglish (US)
Pages (from-to)544-546
Number of pages3
JournalAmerican Journal of Neuroradiology
Issue number3
StatePublished - May 1983

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology


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