Silent new brain lesions: Innocent bystander or guilty party?

Eun Jae Lee, Dong Wha Kang, Steven Warach

Research output: Contribution to journalReview articlepeer-review

23 Scopus citations


With the advances in magnetic resonance imaging, previously unrecognized small brain lesions, which are mostly asymptomatic, have been increasingly detected. Diffusion-weighted imaging can identify small ischemic strokes, while gradient echo T2* imaging and susceptibility-weighted imaging can reveal tiny hemorrhagic strokes (microbleeds). In this article, we review silent brain lesions appearing soon after acute stroke events, including silent new ischemic lesions and microbleeds appearing 1) after acute ischemic stroke and 2) after acute intracerebral hemorrhage. Moreover, we briefly discuss the clinical implications of these silent new brain lesions.

Original languageEnglish (US)
Pages (from-to)38-49
Number of pages12
JournalJournal of Stroke
Issue number1
StatePublished - 2016


  • New ischemic lesions
  • New microbleeds
  • Silent brain lesions

ASJC Scopus subject areas

  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine


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