Silanol: A traceless directing group for Pd-catalyzed o -alkenylation of phenols

Chunhui Huang, Buddhadeb Chattopadhyay, Vladimir Gevorgyan

Research output: Contribution to journalArticlepeer-review

239 Scopus citations


A silanol-directed, Pd(II)-catalyzed C-H alkenylation of phenols is reported. This work features silanol, as a novel traceless directing group, and a directed o-C-H alkenylation of phenols. This new method allows for efficient synthesis of diverse alkenylated phenols, including an estrone derivative.

Original languageEnglish (US)
Pages (from-to)12406-12409
Number of pages4
JournalJournal of the American Chemical Society
Issue number32
StatePublished - Aug 17 2011
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • General Chemistry
  • Biochemistry
  • Colloid and Surface Chemistry


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