Sex differences in the distribution of EEG frequencies during sleep: unipolar depressed outpatients

Roseanne Armitage; Angela Hudson; Madhukar Trivedi; A. John Rush

doi:10.1016/0165-0327(95)00009-C

Sex differences in the distribution of EEG frequencies during sleep: unipolar depressed outpatients

Roseanne Armitage, Angela Hudson, Madhukar Trivedi, A. John Rush

Research output: Contribution to journal › Article › peer-review

47 Scopus citations

Abstract

Sex differences in period-amplitude-analysed (PAA) sleep EEG activity were evaluated in 20 symptomatic, unmedicated, unipolar, depressed outpatients. 19 20 PAA measures showed significant gender main effects or interactions. Overall, depressed females showed a higher incidence and amplitude of fast frequency, beta activity than males, particularly in the right hemisphere. Moreover, gender effects were also evident in sleep-stage-independent analysis of PAA measures. These findings are in striking contrast to normal controls for whom only slow-frequency activity differentiates males from females. These findings suggest that sex differences are stronger in depressed patients than those observed in normals and that these effects are more pronounced than age-related changes in sleep EEG activity.

Original language	English (US)
Pages (from-to)	121-129
Number of pages	9
Journal	Journal of affective disorders
Volume	34
Issue number	2
DOIs	https://doi.org/10.1016/0165-0327(95)00009-C
State	Published - May 17 1995

Keywords

Computer analysis
Depression
Gender
Period-amplitude analysis
Sleep EEG

ASJC Scopus subject areas

Clinical Psychology
Psychiatry and Mental health

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10.1016/0165-0327(95)00009-C

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abstract = "Sex differences in period-amplitude-analysed (PAA) sleep EEG activity were evaluated in 20 symptomatic, unmedicated, unipolar, depressed outpatients. 19 20 PAA measures showed significant gender main effects or interactions. Overall, depressed females showed a higher incidence and amplitude of fast frequency, beta activity than males, particularly in the right hemisphere. Moreover, gender effects were also evident in sleep-stage-independent analysis of PAA measures. These findings are in striking contrast to normal controls for whom only slow-frequency activity differentiates males from females. These findings suggest that sex differences are stronger in depressed patients than those observed in normals and that these effects are more pronounced than age-related changes in sleep EEG activity.",

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AU - Armitage, Roseanne

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AU - Trivedi, Madhukar

AU - Rush, A. John

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AB - Sex differences in period-amplitude-analysed (PAA) sleep EEG activity were evaluated in 20 symptomatic, unmedicated, unipolar, depressed outpatients. 19 20 PAA measures showed significant gender main effects or interactions. Overall, depressed females showed a higher incidence and amplitude of fast frequency, beta activity than males, particularly in the right hemisphere. Moreover, gender effects were also evident in sleep-stage-independent analysis of PAA measures. These findings are in striking contrast to normal controls for whom only slow-frequency activity differentiates males from females. These findings suggest that sex differences are stronger in depressed patients than those observed in normals and that these effects are more pronounced than age-related changes in sleep EEG activity.

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Sex differences in the distribution of EEG frequencies during sleep: unipolar depressed outpatients

Abstract

Keywords

ASJC Scopus subject areas

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