Abstract
Bupropion is an increasingly prescribed agent to aid in smoking cessation. However it has important drug-drug interactions related to the cytochrome P450 system. One of these is its inhibition of the metabolism of the commonly used beta-blocker, metoprolol. The authors describe a case of severe bradycardia related to the addition of bupropion to the medical regimen of a patient on metoprolol.
Original language | English (US) |
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Pages (from-to) | 329-330 |
Number of pages | 2 |
Journal | Cardiovascular Drugs and Therapy |
Volume | 18 |
Issue number | 4 |
DOIs | |
State | Published - Jul 2004 |
Keywords
- bradycardia
- bupropion
- cytochrome P450
- metoprolol
ASJC Scopus subject areas
- Pharmacology
- Cardiology and Cardiovascular Medicine
- Pharmacology (medical)