Serum Sickness

Joe W. Matthews; H. Michael Belmont; Peter B. Dent; Thomas J. Lawley; Kim B. Yancey; Leonard Bielory; Neal Young; Pedro Gascon; Michael M. Frank

doi:10.1056/NEJM198505163122015

Serum Sickness

Joe W. Matthews, H. Michael Belmont, Peter B. Dent, Thomas J. Lawley, Kim B. Yancey, Leonard Bielory, Neal Young, Pedro Gascon, Michael M. Frank

Research output: Contribution to journal › Letter › peer-review

1 Scopus citations

Abstract

To the Editor: Neither the article by Lawley et al. (Nov. 29 issue)* nor the accompanying editorial made any mention of the role of IgE in serum-sickness reactions. IgE is known to cause both immediate and delayed reactions and also to form immune complexes. Although IgE itself does not activate complement, perhaps the immune complexes of IgE can activate complement. Would the authors please comment on the role of IgE in the pathogenesis of serum sickness?.

Original language	English (US)
Pages (from-to)	1327-1328
Number of pages	2
Journal	New England Journal of Medicine
Volume	312
Issue number	20
DOIs	https://doi.org/10.1056/NEJM198505163122015
State	Published - May 16 1985

ASJC Scopus subject areas

Medicine(all)

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10.1056/NEJM198505163122015

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title = "Serum Sickness",

abstract = "To the Editor: Neither the article by Lawley et al. (Nov. 29 issue)* nor the accompanying editorial made any mention of the role of IgE in serum-sickness reactions. IgE is known to cause both immediate and delayed reactions and also to form immune complexes. Although IgE itself does not activate complement, perhaps the immune complexes of IgE can activate complement. Would the authors please comment on the role of IgE in the pathogenesis of serum sickness?.",

author = "Matthews, {Joe W.} and Belmont, {H. Michael} and Dent, {Peter B.} and Lawley, {Thomas J.} and Yancey, {Kim B.} and Leonard Bielory and Neal Young and Pedro Gascon and Frank, {Michael M.}",

year = "1985",

month = may,

day = "16",

doi = "10.1056/NEJM198505163122015",

language = "English (US)",

volume = "312",

pages = "1327--1328",

journal = "New England Journal of Medicine",

issn = "0028-4793",

publisher = "Massachussetts Medical Society",

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TY - JOUR

T1 - Serum Sickness

AU - Matthews, Joe W.

AU - Belmont, H. Michael

AU - Dent, Peter B.

AU - Lawley, Thomas J.

AU - Yancey, Kim B.

AU - Bielory, Leonard

AU - Young, Neal

AU - Gascon, Pedro

AU - Frank, Michael M.

PY - 1985/5/16

Y1 - 1985/5/16

N2 - To the Editor: Neither the article by Lawley et al. (Nov. 29 issue)* nor the accompanying editorial made any mention of the role of IgE in serum-sickness reactions. IgE is known to cause both immediate and delayed reactions and also to form immune complexes. Although IgE itself does not activate complement, perhaps the immune complexes of IgE can activate complement. Would the authors please comment on the role of IgE in the pathogenesis of serum sickness?.

AB - To the Editor: Neither the article by Lawley et al. (Nov. 29 issue)* nor the accompanying editorial made any mention of the role of IgE in serum-sickness reactions. IgE is known to cause both immediate and delayed reactions and also to form immune complexes. Although IgE itself does not activate complement, perhaps the immune complexes of IgE can activate complement. Would the authors please comment on the role of IgE in the pathogenesis of serum sickness?.

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U2 - 10.1056/NEJM198505163122015

DO - 10.1056/NEJM198505163122015

M3 - Letter

C2 - 3873007

AN - SCOPUS:0021811819

SN - 0028-4793

VL - 312

SP - 1327

EP - 1328

JO - New England Journal of Medicine

JF - New England Journal of Medicine

IS - 20

ER -

Serum Sickness

Abstract

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