The adsorption chromatography of purines and related heterocyclic compounds on Sephadex G-10 was investigated under different conditions of pH, ionic strength and flow rate and found to give excellent separations. The elution volumes were highly reproducible and recovery quantitative. A relation between a log function of the elution volumes and substituents on the purine ring was shown and the additivity of the resulting Δ log V6° values used to predict elution volumes. Some analytical and preparative applications have been undertaken.
|Original language||English (US)|
|Number of pages||14|
|Journal||Journal of Chromatography A|
|State||Published - 1968|
ASJC Scopus subject areas
- Analytical Chemistry
- Organic Chemistry