Science to practice: Molecular targeting with SPECT/CT and MR imaging in oncology-integration of functional and structural imaging

Rathan M. Subramaniam

doi:10.1148/radiol.12122734

Science to practice: Molecular targeting with SPECT/CT and MR imaging in oncology-integration of functional and structural imaging

Rathan M. Subramaniam

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Nayak et al (1) utilized single photon emission computed tomography (SPECT), magnetic resonance (MR) imaging and radiolabeled anti-human epidermal growth factor receptor (HER) 1 and 2 targeted monoclonal antibodies to demonstrate HER cell surface expression in malignant pleural mesothelioma (MPM) in mouse models; translating the integration of functional and structural imaging with radiolabeled targeted molecular probes will potentially enable better selection of patients and more effective therapeutic delivery, with fewer adverse effects and more cost effectiveness, in the era of personalized medicine.

Original language	English (US)
Pages (from-to)	1-3
Number of pages	3
Journal	Radiology
Volume	267
Issue number	1
DOIs	https://doi.org/10.1148/radiol.12122734
State	Published - Apr 1 2013

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1148/radiol.12122734

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abstract = "Nayak et al (1) utilized single photon emission computed tomography (SPECT), magnetic resonance (MR) imaging and radiolabeled anti-human epidermal growth factor receptor (HER) 1 and 2 targeted monoclonal antibodies to demonstrate HER cell surface expression in malignant pleural mesothelioma (MPM) in mouse models; translating the integration of functional and structural imaging with radiolabeled targeted molecular probes will potentially enable better selection of patients and more effective therapeutic delivery, with fewer adverse effects and more cost effectiveness, in the era of personalized medicine.",

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AB - Nayak et al (1) utilized single photon emission computed tomography (SPECT), magnetic resonance (MR) imaging and radiolabeled anti-human epidermal growth factor receptor (HER) 1 and 2 targeted monoclonal antibodies to demonstrate HER cell surface expression in malignant pleural mesothelioma (MPM) in mouse models; translating the integration of functional and structural imaging with radiolabeled targeted molecular probes will potentially enable better selection of patients and more effective therapeutic delivery, with fewer adverse effects and more cost effectiveness, in the era of personalized medicine.

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Science to practice: Molecular targeting with SPECT/CT and MR imaging in oncology-integration of functional and structural imaging

Abstract

ASJC Scopus subject areas

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