Schizophrenia

Carol A. Tamminga; Deborah C. Medoff; Gunvant Thaker

doi:10.1007/978-1-59259-963-9_128

Schizophrenia

Carol A. Tamminga, Deborah C. Medoff, Gunvant Thaker

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Despite a broad knowledge base about the pathology of schizophrenia, albeit fragmented and often inconsistent, no theme has emerged to link the illness with its molecular pathophysiology. There is insufficient certainty and consistency of findings to identify the critical molecular target on which to base therapeutic discovery. The most limiting aspect of schizophrenia therapeutics is this lack of critical knowledge with respect to its target pathophysiology, on which therapeutic strategies could be developed.

Original language	English (US)
Title of host publication	Principles of Molecular Medicine
Publisher	Humana Press
Pages	1211-1219
Number of pages	9
ISBN (Print)	9781588292025
DOIs	https://doi.org/10.1007/978-1-59259-963-9_128
State	Published - Dec 1 2006

Keywords

Central nervous system
electroencephalographic
homovanillic acid
magnetic resonance imaging
regional cerebral blood flow
schizophrenia

ASJC Scopus subject areas

Medicine(all)

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10.1007/978-1-59259-963-9_128

Cite this

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AU - Thaker, Gunvant

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AB - Despite a broad knowledge base about the pathology of schizophrenia, albeit fragmented and often inconsistent, no theme has emerged to link the illness with its molecular pathophysiology. There is insufficient certainty and consistency of findings to identify the critical molecular target on which to base therapeutic discovery. The most limiting aspect of schizophrenia therapeutics is this lack of critical knowledge with respect to its target pathophysiology, on which therapeutic strategies could be developed.

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KW - homovanillic acid

KW - magnetic resonance imaging

KW - regional cerebral blood flow

KW - schizophrenia

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Schizophrenia

Abstract

Keywords

ASJC Scopus subject areas

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