Carol A. Tamminga, Deborah C. Medoff, Gunvant Thaker

Research output: Chapter in Book/Report/Conference proceedingChapter


Despite a broad knowledge base about the pathology of schizophrenia, albeit fragmented and often inconsistent, no theme has emerged to link the illness with its molecular pathophysiology. There is insufficient certainty and consistency of findings to identify the critical molecular target on which to base therapeutic discovery. The most limiting aspect of schizophrenia therapeutics is this lack of critical knowledge with respect to its target pathophysiology, on which therapeutic strategies could be developed.

Original languageEnglish (US)
Title of host publicationPrinciples of Molecular Medicine
PublisherHumana Press
Number of pages9
ISBN (Print)9781588292025
StatePublished - Dec 1 2006


  • Central nervous system
  • electroencephalographic
  • homovanillic acid
  • magnetic resonance imaging
  • regional cerebral blood flow
  • schizophrenia

ASJC Scopus subject areas

  • Medicine(all)


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