TY - JOUR
T1 - RNA polymerase II transcription factor SIII
T2 - I. Identification, purification, and properties
AU - Bradsher, John N.
AU - Jackson, Kenneth W.
AU - Conaway, Ronald C.
AU - Conaway, Joan Weliky
PY - 1993/12/5
Y1 - 1993/12/5
N2 - A transcription factor that stimulates synthesis of accurately initiated transcripts by RNA polymerase II has been identified and purified to apparent homogeneity from rat liver nuclear extracts. This factor, which we designate SIII, has a native molecular mass of ∼140 kDa and is composed of three polypeptides of 110, 18, and 15 kDa. All three polypeptides are required to reconstitute SIII transcriptional activity. SIII appears distinct from previously identified mammalian transcription factors.
AB - A transcription factor that stimulates synthesis of accurately initiated transcripts by RNA polymerase II has been identified and purified to apparent homogeneity from rat liver nuclear extracts. This factor, which we designate SIII, has a native molecular mass of ∼140 kDa and is composed of three polypeptides of 110, 18, and 15 kDa. All three polypeptides are required to reconstitute SIII transcriptional activity. SIII appears distinct from previously identified mammalian transcription factors.
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M3 - Article
C2 - 8244996
AN - SCOPUS:0027378324
SN - 0021-9258
VL - 268
SP - 25587
EP - 25593
JO - Journal of Biological Chemistry
JF - Journal of Biological Chemistry
IS - 34
ER -