TY - JOUR
T1 - Rise of a Cereal Killer
T2 - The Biology of Magnaporthe oryzae Biotrophic Growth
AU - Fernandez, Jessie
AU - Orth, Kim
N1 - Funding Information:
This work was supported by the Welch Foundation grant I-1561 and Once Upon a Time…Foundation. JF was funded by the Microbiology Training (grant T32 AI007520-17) and the Once Upon a Time…Foundation. K.O. is a Burroughs Welcome Investigator in Pathogenesis of Infectious Disease, a Beckman Young Investigator, and a W.W. Caruth, Jr., Biomedical Scholar, and has an Earl A. Forsythe Chair in Biomedical Science. We thank the members of the Orth laboratory for thoughtful discussion and revision of this manuscript. We are very thankful to Dor Salomon and Richard A. Wilson for their critical review of our manuscript.
Publisher Copyright:
© 2017 Elsevier Ltd
PY - 2018/7
Y1 - 2018/7
N2 - The rice blast fungus, Magnaporthe oryzae, causes one of the most destructive diseases of cultivated rice in the world. Infections caused by this recalcitrant pathogen lead to the annual destruction of approximately 10–30% of the rice harvested globally. The fungus undergoes extensive developmental changes to be able to break into plant cells, build elaborate infection structures, and proliferate inside host cells without causing visible disease symptoms. From a molecular standpoint, we are still in the infancy of understanding how M. oryzae manipulates the host during this complex multifaceted infection. Here, we describe recent advances in our understanding of the cell biology of M. oryzae biotrophic interaction and key molecular factors required for the disease establishment in rice cells.
AB - The rice blast fungus, Magnaporthe oryzae, causes one of the most destructive diseases of cultivated rice in the world. Infections caused by this recalcitrant pathogen lead to the annual destruction of approximately 10–30% of the rice harvested globally. The fungus undergoes extensive developmental changes to be able to break into plant cells, build elaborate infection structures, and proliferate inside host cells without causing visible disease symptoms. From a molecular standpoint, we are still in the infancy of understanding how M. oryzae manipulates the host during this complex multifaceted infection. Here, we describe recent advances in our understanding of the cell biology of M. oryzae biotrophic interaction and key molecular factors required for the disease establishment in rice cells.
KW - apoplastic effectors.
KW - appressorium
KW - cytoplasmic effectors
KW - rice blast
UR - http://www.scopus.com/inward/record.url?scp=85040792193&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85040792193&partnerID=8YFLogxK
U2 - 10.1016/j.tim.2017.12.007
DO - 10.1016/j.tim.2017.12.007
M3 - Review article
C2 - 29395728
AN - SCOPUS:85040792193
SN - 0966-842X
VL - 26
SP - 582
EP - 597
JO - Trends in Microbiology
JF - Trends in Microbiology
IS - 7
ER -