Rhodium-catalyzed annulation of N-benzoylsulfonamide with isocyanide through C-H activation

Chen Zhu; Weiqing Xie; J R Falck

doi:10.1002/chem.201102475

Rhodium-catalyzed annulation of N-benzoylsulfonamide with isocyanide through C-H activation

Chen Zhu, Weiqing Xie, J R Falck

Biochemistry

Research output: Contribution to journal › Article › peer-review

137 Scopus citations

Abstract

The first rhodium-catalyzed annulation of N-benzoylsulfonamide (1) with isocyanide (2) through CiH activation is described. The transformation is broadly compatible with N-benzoylsulfonamides as well as isocyanides with different electronic properties. From a practical point of view, this method provides the most straightforward approach to a series of 3-(imino) isoindolinones (3). Ts=4-toluenesulfonyl.

Original language	English (US)
Pages (from-to)	12591-12595
Number of pages	5
Journal	Chemistry - A European Journal
Volume	17
Issue number	45
DOIs	https://doi.org/10.1002/chem.201102475
State	Published - Nov 4 2011

Keywords

CiH activation
annulations
heterocycles
isocyanide
rhodium

ASJC Scopus subject areas

Catalysis
Organic Chemistry

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10.1002/chem.201102475

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title = "Rhodium-catalyzed annulation of N-benzoylsulfonamide with isocyanide through C-H activation",

abstract = "The first rhodium-catalyzed annulation of N-benzoylsulfonamide (1) with isocyanide (2) through CiH activation is described. The transformation is broadly compatible with N-benzoylsulfonamides as well as isocyanides with different electronic properties. From a practical point of view, this method provides the most straightforward approach to a series of 3-(imino) isoindolinones (3). Ts=4-toluenesulfonyl.",

keywords = "CiH activation, annulations, heterocycles, isocyanide, rhodium",

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year = "2011",

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AU - Zhu, Chen

AU - Xie, Weiqing

AU - Falck, J R

PY - 2011/11/4

Y1 - 2011/11/4

N2 - The first rhodium-catalyzed annulation of N-benzoylsulfonamide (1) with isocyanide (2) through CiH activation is described. The transformation is broadly compatible with N-benzoylsulfonamides as well as isocyanides with different electronic properties. From a practical point of view, this method provides the most straightforward approach to a series of 3-(imino) isoindolinones (3). Ts=4-toluenesulfonyl.

AB - The first rhodium-catalyzed annulation of N-benzoylsulfonamide (1) with isocyanide (2) through CiH activation is described. The transformation is broadly compatible with N-benzoylsulfonamides as well as isocyanides with different electronic properties. From a practical point of view, this method provides the most straightforward approach to a series of 3-(imino) isoindolinones (3). Ts=4-toluenesulfonyl.

KW - CiH activation

KW - annulations

KW - heterocycles

KW - isocyanide

KW - rhodium

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JO - Chemistry - A European Journal

JF - Chemistry - A European Journal

IS - 45

ER -

Rhodium-catalyzed annulation of N-benzoylsulfonamide with isocyanide through C-H activation

Abstract

Keywords

ASJC Scopus subject areas

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