TY - JOUR
T1 - Review of Florida red tide and human health effects
AU - Fleming, Lora E.
AU - Kirkpatrick, Barbara
AU - Backer, Lorraine C.
AU - Walsh, Cathy J.
AU - Nierenberg, Kate
AU - Clark, John
AU - Reich, Andrew
AU - Hollenbeck, Julie
AU - Benson, Janet
AU - Cheng, Yung Sung
AU - Naar, Jerome
AU - Pierce, Richard
AU - Bourdelais, Andrea J.
AU - Abraham, William M.
AU - Kirkpatrick, Gary
AU - Zaias, Julia
AU - Wanner, Adam
AU - Mendes, Eliana
AU - Shalat, Stuart
AU - Hoagland, Porter
AU - Stephan, Wendy
AU - Bean, Judy
AU - Watkins, Sharon
AU - Clarke, Tainya
AU - Byrne, Margaret
AU - Baden, Daniel G.
N1 - Funding Information:
This study was funded in part by the National Institute for Environmental Health Sciences (NIEHS) P01 ES10594, NIEHS R21 ES014717, NIEHS P30 ES005022, and NIEHS R21 ES017413; the Centers for Disease Control and Prevention (CDC); the Florida Department of Health; the National Science Foundation (NSF)-NIEHS Oceans and Human Health Center at the University of Miami Rosenstiel School of Marine and Atmospheric Sciences (NSF OCE0432368/OCE0911373; NIEHS P50 ES12736); and NSF 1009106.[SS]
PY - 2011/1
Y1 - 2011/1
N2 - This paper reviews the literature describing research performed over the past decade on the known and possible exposures and human health effects associated with Florida red tides. These harmful algal blooms are caused by the dinoflagellate, Karenia brevis, and similar organisms, all of which produce a suite of natural toxins known as brevetoxins. Florida red tide research has benefited from a consistently funded, long-term research program, that has allowed an interdisciplinary team of researchers to focus their attention on this specific environmental issue-one that is critically important to Gulf of Mexico and other coastal communities. This long-term interdisciplinary approach has allowed the team to engage the local community, identify measures to protect public health, take emerging technologies into the field, forge advances in natural products chemistry, and develop a valuable pharmaceutical product. The review includes a brief discussion of the Florida red tide organisms and their toxins, and then focuses on the effects of these toxins on animals and humans, including how these effects predict what we might expect to see in exposed people.
AB - This paper reviews the literature describing research performed over the past decade on the known and possible exposures and human health effects associated with Florida red tides. These harmful algal blooms are caused by the dinoflagellate, Karenia brevis, and similar organisms, all of which produce a suite of natural toxins known as brevetoxins. Florida red tide research has benefited from a consistently funded, long-term research program, that has allowed an interdisciplinary team of researchers to focus their attention on this specific environmental issue-one that is critically important to Gulf of Mexico and other coastal communities. This long-term interdisciplinary approach has allowed the team to engage the local community, identify measures to protect public health, take emerging technologies into the field, forge advances in natural products chemistry, and develop a valuable pharmaceutical product. The review includes a brief discussion of the Florida red tide organisms and their toxins, and then focuses on the effects of these toxins on animals and humans, including how these effects predict what we might expect to see in exposed people.
KW - Brevetoxins
KW - Florida red tide
KW - Harmful algal bloom (HAB)
KW - Karenia brevis
KW - Marine toxin diseases
KW - Neurotoxic fish poisoning
KW - Neurotoxic shellfish poisoning (NSP)
KW - Red tide
KW - Respiratory irritation
KW - Shellfish poisoning
UR - http://www.scopus.com/inward/record.url?scp=78650287679&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78650287679&partnerID=8YFLogxK
U2 - 10.1016/j.hal.2010.08.006
DO - 10.1016/j.hal.2010.08.006
M3 - Review article
C2 - 21218152
AN - SCOPUS:78650287679
SN - 1568-9883
VL - 10
SP - 224
EP - 233
JO - Harmful Algae
JF - Harmful Algae
IS - 2
ER -