Retinoblastoma Tumorigenesis

Michael A. Dyer; Michael A. Dyer; J. William Harbour; J. William Harbour; J. William Harbour

doi:10.1007/978-3-662-43451-2_6

Retinoblastoma Tumorigenesis

Michael A. Dyer, Michael A. Dyer, J. William Harbour, J. William Harbour, J. William Harbour

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Tumorigenesis is a multistep process that involves sequential genetic alterations [1]. Preneoplastic cells must overcome their dependence on extrinsic mitogenic signals, evade apoptosis, prevent degradation of life-span-limiting telomeres, recruit vasculature, and acquire invasive properties to become malignant tumor cells [1].

Original language	English (US)
Title of host publication	Clinical Ophthalmic Oncology
Subtitle of host publication	Retinoblastoma, Second Edition
Publisher	Springer Berlin Heidelberg
Pages	61-68
Number of pages	8
ISBN (Electronic)	9783662434512
ISBN (Print)	9783662434505
DOIs	https://doi.org/10.1007/978-3-662-43451-2_6
State	Published - Jan 1 2015
Externally published	Yes

ASJC Scopus subject areas

General Medicine

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10.1007/978-3-662-43451-2_6

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title = "Retinoblastoma Tumorigenesis",

abstract = "Tumorigenesis is a multistep process that involves sequential genetic alterations [1]. Preneoplastic cells must overcome their dependence on extrinsic mitogenic signals, evade apoptosis, prevent degradation of life-span-limiting telomeres, recruit vasculature, and acquire invasive properties to become malignant tumor cells [1].",

author = "Dyer, {Michael A.} and Dyer, {Michael A.} and Harbour, {J. William} and Harbour, {J. William} and Harbour, {J. William}",

year = "2015",

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doi = "10.1007/978-3-662-43451-2_6",

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EP - 68

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Retinoblastoma Tumorigenesis

Abstract

ASJC Scopus subject areas

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