Retinal Assessment Using In Vivo Electroretinography and Optical Coherence Tomography in Rodent Models of Diabetes

Da Zhao, Pei Ying Lee, Vickie H.Y. Wong, Tomoharu Nishimura, Anh Hoang, Katie K.N. Tran, Anna K. van Koeverden, Brianna C. Afiat, Christine T.O. Nguyen, Bang V. Bui

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Electroretinography and optical coherence tomography imaging allow for non-invasive quantitative assessment of the retina. These approaches have become mainstays for identifying the very earliest impact of hyperglycemia on retinal function and structure in animal models of diabetic eye disease. Moreover, they are essential for assessing the safety and efficacy of novel treatment approaches for diabetic retinopathy. Here, we describe approaches for in vivo electroretinography and optical coherence tomography imaging in rodent models of diabetes.

Original languageEnglish (US)
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages37-48
Number of pages12
DOIs
StatePublished - 2023
Externally publishedYes

Publication series

NameMethods in Molecular Biology
Volume2678
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029

Keywords

  • Electroretinogram
  • In vivo retinal assessment
  • Optical coherence tomography
  • Retinal function
  • Retinal structure
  • Rodents
  • Small animal models

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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