Resistant hypertension

Norman M Kaplan

Research output: Contribution to journalReview articlepeer-review

97 Scopus citations


Hypertension that remains above 140/90 mmHg despite the use of three antihypertensive drugs in a rational combination at full doses and including a diuretic is known as 'resistant'. The percentage of hypertensives whose condition is resistant varies in large part upon the setting: those seen in general practice show a prevalence of perhaps 5%; those seen by nephrologists, probably 50%. This paper reviews the major causes of resistant hypertension and provides specific recommendations for the evaluation and management of patients with this threatening condition.

Original languageEnglish (US)
Pages (from-to)1441-1444
Number of pages4
JournalJournal of hypertension
Issue number8
StatePublished - Aug 2005


  • Resistant hypertension

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine


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