Renal Aspects of Sodium Metabolism in the Fetus and Neonate

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations


The transition from a growing fetus to a newborn infant requires many changes in fluid and electrolyte homeostasis. During gestation, the placenta controls this balance, but once the fetus is born, the kidneys will perform the task of regulating the excretion of water, electrolytes, and solutes, as well as nitrogenous waste products. This chapter will briefly review the factors that regulate the placental exchange of fluid and sodium, as well as the renal developmental changes that occur throughout the growth of the fetus and the subsequent adaptation to life outside of the womb, with a focus on the postnatal development of renal tubular transport.

Original languageEnglish (US)
Title of host publicationNephrology and Fluid/Electrolyte Physiology
Subtitle of host publicationNeonatology Questions and Controversies
Number of pages18
ISBN (Electronic)9780323533676
StatePublished - Jan 1 2018


  • Collecting duct
  • Distal convuluted tubule
  • Proximal tubule
  • Sodium transport
  • Thick ascending limb of Henle
  • Water transport

ASJC Scopus subject areas

  • Medicine(all)


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