Regulation of the RNAPII Pool Is Integral to the DNA Damage Response

Ana Tufegdžić Vidaković; Richard Mitter; Gavin P. Kelly; Michelle Neumann; Michelle Harreman; Marta Rodríguez-Martínez; Anna Herlihy; Juston C. Weems; Stefan Boeing; Vesela Encheva; Liam Gaul; Laura Milligan; David Tollervey; Ronald C. Conaway; Joan W. Conaway; Ambrosius P. Snijders; Aengus Stewart; Jesper Q. Svejstrup

doi:10.1016/j.cell.2020.02.009

Regulation of the RNAPII Pool Is Integral to the DNA Damage Response

Ana Tufegdžić Vidaković, Richard Mitter, Gavin P. Kelly, Michelle Neumann, Michelle Harreman, Marta Rodríguez-Martínez, Anna Herlihy, Juston C. Weems, Stefan Boeing, Vesela Encheva, Liam Gaul, Laura Milligan, David Tollervey, Ronald C. Conaway, Joan W. Conaway, Ambrosius P. Snijders, Aengus Stewart, Jesper Q. Svejstrup

Research output: Contribution to journal › Article › peer-review

120 Scopus citations

Abstract

Control of the pool of available RNA polymerase II shapes how cells respond to UV stress and the efficacy of the resulting damage response.

Original language	English (US)
Pages (from-to)	1245-1261.e21
Journal	Cell
Volume	180
Issue number	6
DOIs	https://doi.org/10.1016/j.cell.2020.02.009
State	Published - Mar 19 2020
Externally published	Yes

Keywords

DNA damage
RNA polymerase II
UV irradiation
transcription
ubiquitin
ubiquitylation

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1016/j.cell.2020.02.009

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Tufegdžić Vidaković, A., Mitter, R., Kelly, G. P., Neumann, M., Harreman, M., Rodríguez-Martínez, M., Herlihy, A., Weems, J. C., Boeing, S., Encheva, V., Gaul, L., Milligan, L., Tollervey, D., Conaway, R. C., Conaway, J. W., Snijders, A. P., Stewart, A., & Svejstrup, J. Q. (2020). Regulation of the RNAPII Pool Is Integral to the DNA Damage Response. Cell, 180(6), 1245-1261.e21. https://doi.org/10.1016/j.cell.2020.02.009

Tufegdžić Vidaković, A, Mitter, R, Kelly, GP, Neumann, M, Harreman, M, Rodríguez-Martínez, M, Herlihy, A, Weems, JC, Boeing, S, Encheva, V, Gaul, L, Milligan, L, Tollervey, D, Conaway, RC, Conaway, JW, Snijders, AP, Stewart, A & Svejstrup, JQ 2020, 'Regulation of the RNAPII Pool Is Integral to the DNA Damage Response', Cell, vol. 180, no. 6, pp. 1245-1261.e21. https://doi.org/10.1016/j.cell.2020.02.009

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title = "Regulation of the RNAPII Pool Is Integral to the DNA Damage Response",

abstract = "Control of the pool of available RNA polymerase II shapes how cells respond to UV stress and the efficacy of the resulting damage response.",

keywords = "DNA damage, RNA polymerase II, UV irradiation, transcription, ubiquitin, ubiquitylation",

author = "{Tufegd{\v z}i{\'c} Vidakovi{\'c}}, Ana and Richard Mitter and Kelly, {Gavin P.} and Michelle Neumann and Michelle Harreman and Marta Rodr{\'i}guez-Mart{\'i}nez and Anna Herlihy and Weems, {Juston C.} and Stefan Boeing and Vesela Encheva and Liam Gaul and Laura Milligan and David Tollervey and Conaway, {Ronald C.} and Conaway, {Joan W.} and Snijders, {Ambrosius P.} and Aengus Stewart and Svejstrup, {Jesper Q.}",

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doi = "10.1016/j.cell.2020.02.009",

language = "English (US)",

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AU - Tufegdžić Vidaković, Ana

AU - Mitter, Richard

AU - Kelly, Gavin P.

AU - Neumann, Michelle

AU - Harreman, Michelle

AU - Rodríguez-Martínez, Marta

AU - Herlihy, Anna

AU - Weems, Juston C.

AU - Boeing, Stefan

AU - Encheva, Vesela

AU - Gaul, Liam

AU - Milligan, Laura

AU - Tollervey, David

AU - Conaway, Ronald C.

AU - Conaway, Joan W.

AU - Snijders, Ambrosius P.

AU - Stewart, Aengus

AU - Svejstrup, Jesper Q.

PY - 2020/3/19

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N2 - Control of the pool of available RNA polymerase II shapes how cells respond to UV stress and the efficacy of the resulting damage response.

AB - Control of the pool of available RNA polymerase II shapes how cells respond to UV stress and the efficacy of the resulting damage response.

KW - DNA damage

KW - RNA polymerase II

KW - UV irradiation

KW - transcription

KW - ubiquitin

KW - ubiquitylation

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Regulation of the RNAPII Pool Is Integral to the DNA Damage Response

Abstract

Keywords

ASJC Scopus subject areas

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