Redox State Controls Phase Separation of the Yeast Ataxin-2 Protein via Reversible Oxidation of Its Methionine-Rich Low-Complexity Domain

Medicine & Life Sciences

• Ataxin-2 100%
• Fungal Proteins 70%
• Methionine 58%
• Oxidation-Reduction 53%
• Phase Transition 47%
• Polymers 33%
• methionine sulfoxide reductase 32%
• Aromatic Amino Acids 26%
• Mechanistic Target of Rapamycin Complex 1 23%
• Phenylalanine 20%
• Protein Domains 18%
• Hydrogen Peroxide 18%
• Tyrosine 17%
• Mitochondria 15%
• Gels 15%
• Yeasts 15%
• Enzymes 10%
• In Vitro Techniques 8%
• Proteins 6%

Chemical Compounds

• Methionine Residue 74%
• Redox State 64%
• Methionine 57%
• Phase Separation 48%
• Phenylalanine Residue 39%
• Aromatic Amino Acid 32%
• Tyrosine Residue 32%
• Sulfoxide 27%
• Oxidation Reaction 25%
• Protein 23%
• Hydrogen Peroxide 21%