Reconstructive septorhinoplasty in radiation-induced reactive bone dysplasia

Nkechi N. Nwabueze, Justin R. Shinn, Scott Owen, W. Russell Ries, Scott J. Stephan

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Objective: To describe a complicated external septorhinoplasty in a case of nasal adenocarcinoma radiation-induced reactive bone dysplasia. Case description: We describe a 40-year-old female with high-grade sinonasal adenocarcinoma who was treated with induction chemotherapy and radiation. The patient eventually presented with findings consistent with radiation-induced osseous changes that mimicked fibrous dysplasia. She was successfully treated with external septorhinoplasty for restoration of function and improved cosmesis. To our knowledge, this is one of few reported cases of craniofacial fibrous dysplasia caused by radiation therapy. Conclusions: Fibrous dysplasia is a disease that can lead to significant debilitation in patients, however radiation-induced fibrous dysplasia is a rarely reported disease with no clear consensus guidelines. Select patients can be treated surgically to provide symptomatic relief and improved cosmesis.

Original languageEnglish (US)
Article number100131
JournalOtolaryngology Case Reports
StatePublished - Nov 2019
Externally publishedYes


  • Fibrodysplasia
  • Fibrous dysplasia
  • Saddle nose
  • Septorhinoplasty

ASJC Scopus subject areas

  • Otorhinolaryngology


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