@article{07e7902c28cc42e58734cae5eb567f1c,
title = "Recent developments for the efficient crystallographic refinement of macromolecular structures",
abstract = "Macromolecular crystallographic refinement has recently been made more efficient by the use of cross-validated maximum likelihood targets and torsion-angle molecular dynamics simulated annealing. In combination with automated model building methods, the amount of manual intervention required to complete and refine a structure is greatly reduced.",
author = "Br{\"u}nger, {Axel T.} and Adams, {Paul D.} and Rice, {Luke M.}",
note = "Funding Information: Many of the computational developments discussed in this review are implemented in the software suite Crystallography and NMR System \[38{"}\]. A prereleasc of this software suite is available upon request. LMR is a Howard Hughes Mcdical Institute predoctoral fellow. This work was funded in part by grants from the National Science Foundation to ATB (B1R 9514819 and ASC 93-181159).",
year = "1998",
month = oct,
doi = "10.1016/S0959-440X(98)80152-8",
language = "English (US)",
volume = "8",
pages = "606--611",
journal = "Current Opinion in Structural Biology",
issn = "0959-440X",
publisher = "Elsevier Limited",
number = "5",
}