TY - JOUR
T1 - Rapidly fatal acute bacterial myocarditis in a nonneutropenic child with acute lymphoblastic leukemia in remission
AU - Scothorn, Douglas J.
AU - Winick, Naomi J.
AU - Timmons, Charles F.
AU - Aquino, Naomiand Victor M
PY - 2002/11
Y1 - 2002/11
N2 - The authors report a fatal case of acute bacterial myocarditis in a nonneutropenic child with acute lymphoblastic leukemia. She was admitted to the hospital with a urinary tract infection resulting from Klebsiella pneumoniae and remained persistently febrile despite resolution of the infection. On hospital day 4 signs of acute cardiac failure developed. Despite aggressive resuscitation measures, she died. Pathologic examination revealed the cause of death to be bacterial myocarditis. In addition, she was found to have a generalized decrease in her serum immunoglobulin levels. Acute bacterial myocarditis in patients with malignancy has been rarely reported. The rapid clinical deterioration and death in the patient in this report is particularly interesting.
AB - The authors report a fatal case of acute bacterial myocarditis in a nonneutropenic child with acute lymphoblastic leukemia. She was admitted to the hospital with a urinary tract infection resulting from Klebsiella pneumoniae and remained persistently febrile despite resolution of the infection. On hospital day 4 signs of acute cardiac failure developed. Despite aggressive resuscitation measures, she died. Pathologic examination revealed the cause of death to be bacterial myocarditis. In addition, she was found to have a generalized decrease in her serum immunoglobulin levels. Acute bacterial myocarditis in patients with malignancy has been rarely reported. The rapid clinical deterioration and death in the patient in this report is particularly interesting.
KW - Acute lymphoblastic leukemia
KW - Bacterial myocarditis
KW - Klebsiella pneumoniae
UR - http://www.scopus.com/inward/record.url?scp=0036843159&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036843159&partnerID=8YFLogxK
U2 - 10.1097/00043426-200211000-00012
DO - 10.1097/00043426-200211000-00012
M3 - Article
C2 - 12439040
AN - SCOPUS:0036843159
SN - 1077-4114
VL - 24
SP - 662
EP - 665
JO - Journal of Pediatric Hematology/Oncology
JF - Journal of Pediatric Hematology/Oncology
IS - 8
ER -