Radiosynthesis and Preliminary Evaluation of [¹¹C]SSI-4 for the Positron Emission Tomography Imaging of Stearoyl CoA Desaturase 1

Medicine & Life Sciences

• Stearoyl-CoA Desaturase 87%
• Positron-Emission Tomography 54%
• Hepatocellular Carcinoma 20%
• Renal Cell Carcinoma 16%
• Heterografts 14%
• Cell Line 14%
• Fatty Acids 14%
• Neoplasms 13%
• piperidine 11%
• Monounsaturated Fatty Acids 11%
• Brown Adipose Tissue 10%
• Lacrimal Apparatus 10%
• Animals 8%
• Radioactivity 8%
• Urea 7%
• Cold Temperature 7%
• In Vitro Techniques 7%
• High Pressure Liquid Chromatography 6%
• Ligands 5%
• Phenotype 5%
• Injections 4%
• Enzymes 4%
• Liver 4%
• Therapeutics 1%

Chemical Compounds

• Stearoyl-CoA 100%
• Positron 68%
• Radiochemical Yield 20%
• Monounsaturated Fatty Acid 11%
• Saturated Fatty Acid 10%
• Brown 8%
• Radioactivity 8%
• Fat 8%
• Fatty Acid 6%
• Urea 6%
• Pharmacological Metabolism 6%
• Kd 6%
• Purification 5%
• Block Like Crystal 5%
• Purity 4%
• Ligand 3%
• Time 2%