Quantitative comparison of spatial resolution in step-and-shoot and continuous motion digital breast tomosynthesis

Muhammad U. Ghani; Di Wu; Molly D. Wong; Liqiang Ren; Bin Zheng; Kai Yang; Xizeng Wu; Hong Liu

doi:10.1117/12.2216102

Quantitative comparison of spatial resolution in step-and-shoot and continuous motion digital breast tomosynthesis

Muhammad U. Ghani, Di Wu, Molly D. Wong, Liqiang Ren, Bin Zheng, Kai Yang, Xizeng Wu, Hong Liu

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

4 Scopus citations

Abstract

This study compares the spatial resolution in step-and-shoot and continuous motion acquisition modes of digital tomosynthesis using a bench-top prototype designed for breast phantoms imaging. The prototype employs a flat panel detector with a 50 μm pixel pitch, a micro focus x-ray tube and a motorized stage. A sharp metal edge with a thickness of 0.2 mm was used to measure the modulation transfer function (MTF). The edge was rotated from -7.5° to +7.5° with 1.5° increments to acquire 11 angular projections using 40 kVp, 500 μA with 5.55 s per projection. In continuous motion mode, the motorized stage moved the test object for the whole exposure time at a speed of 0.377 mm/s. The impact of acquisition speed in continuous DBT was also investigated, and a high speed of 0.753 mm/s was used. In step-and-shoot mode, the cutoff frequencies (10% MTF) in projection view (0°) and reconstructed DBT slices were 5.55 lp/mm and 4.95 lp/mm. Spatial resolution dropped in the continuous motion mode of the DBT due to the blur caused by the rotation of the stage and the cutoff frequencies reduced to 3.6 lp/mm and 3.18 lp/mm in the projection view (0°) and reconstructed DBT slices. At high rotational speed in continuous motion mode, the cutoff frequencies in the DBT slices dropped by 17 % to 2.65 lp/mm. Rotational speed of the rotation stage and spatial resolution are interconnected. Hence, reducing the motion blur in the continuous acquisition mode is important to maintain high spatial resolution for diagnostic purposes.

Original language	English (US)
Title of host publication	Medical Imaging 2016
Subtitle of host publication	Physics of Medical Imaging
Editors	Despina Kontos, Joseph Y. Lo, Thomas G. Flohr
Publisher	SPIE
ISBN (Electronic)	9781510600188
DOIs	https://doi.org/10.1117/12.2216102
State	Published - 2016
Externally published	Yes
Event	Medical Imaging 2016: Physics of Medical Imaging - San Diego, United States Duration: Feb 28 2016 → Mar 2 2016

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	9783
ISSN (Print)	1605-7422

Other

Other	Medical Imaging 2016: Physics of Medical Imaging
Country/Territory	United States
City	San Diego
Period	2/28/16 → 3/2/16

Keywords

Digital Breast Tomosynthesis
continuous motion
spatial resolution
step-and-shoot

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics
Biomaterials
Radiology Nuclear Medicine and imaging

Access to Document

10.1117/12.2216102

Cite this

Ghani, M. U., Wu, D., Wong, M. D., Ren, L., Zheng, B., Yang, K., Wu, X., & Liu, H. (2016). Quantitative comparison of spatial resolution in step-and-shoot and continuous motion digital breast tomosynthesis. In D. Kontos, J. Y. Lo, & T. G. Flohr (Eds.), Medical Imaging 2016: Physics of Medical Imaging Article 97836D (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 9783). SPIE. https://doi.org/10.1117/12.2216102

Quantitative comparison of spatial resolution in step-and-shoot and continuous motion digital breast tomosynthesis. / Ghani, Muhammad U.; Wu, Di; Wong, Molly D. et al.
Medical Imaging 2016: Physics of Medical Imaging. ed. / Despina Kontos; Joseph Y. Lo; Thomas G. Flohr. SPIE, 2016. 97836D (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 9783).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Ghani, MU, Wu, D, Wong, MD, Ren, L, Zheng, B, Yang, K, Wu, X & Liu, H 2016, Quantitative comparison of spatial resolution in step-and-shoot and continuous motion digital breast tomosynthesis. in D Kontos, JY Lo & TG Flohr (eds), Medical Imaging 2016: Physics of Medical Imaging., 97836D, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 9783, SPIE, Medical Imaging 2016: Physics of Medical Imaging, San Diego, United States, 2/28/16. https://doi.org/10.1117/12.2216102

Ghani MU, Wu D, Wong MD, Ren L, Zheng B, Yang K et al. Quantitative comparison of spatial resolution in step-and-shoot and continuous motion digital breast tomosynthesis. In Kontos D, Lo JY, Flohr TG, editors, Medical Imaging 2016: Physics of Medical Imaging. SPIE. 2016. 97836D. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). doi: 10.1117/12.2216102

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abstract = "This study compares the spatial resolution in step-and-shoot and continuous motion acquisition modes of digital tomosynthesis using a bench-top prototype designed for breast phantoms imaging. The prototype employs a flat panel detector with a 50 μm pixel pitch, a micro focus x-ray tube and a motorized stage. A sharp metal edge with a thickness of 0.2 mm was used to measure the modulation transfer function (MTF). The edge was rotated from -7.5° to +7.5° with 1.5° increments to acquire 11 angular projections using 40 kVp, 500 μA with 5.55 s per projection. In continuous motion mode, the motorized stage moved the test object for the whole exposure time at a speed of 0.377 mm/s. The impact of acquisition speed in continuous DBT was also investigated, and a high speed of 0.753 mm/s was used. In step-and-shoot mode, the cutoff frequencies (10% MTF) in projection view (0°) and reconstructed DBT slices were 5.55 lp/mm and 4.95 lp/mm. Spatial resolution dropped in the continuous motion mode of the DBT due to the blur caused by the rotation of the stage and the cutoff frequencies reduced to 3.6 lp/mm and 3.18 lp/mm in the projection view (0°) and reconstructed DBT slices. At high rotational speed in continuous motion mode, the cutoff frequencies in the DBT slices dropped by 17 % to 2.65 lp/mm. Rotational speed of the rotation stage and spatial resolution are interconnected. Hence, reducing the motion blur in the continuous acquisition mode is important to maintain high spatial resolution for diagnostic purposes.",

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AB - This study compares the spatial resolution in step-and-shoot and continuous motion acquisition modes of digital tomosynthesis using a bench-top prototype designed for breast phantoms imaging. The prototype employs a flat panel detector with a 50 μm pixel pitch, a micro focus x-ray tube and a motorized stage. A sharp metal edge with a thickness of 0.2 mm was used to measure the modulation transfer function (MTF). The edge was rotated from -7.5° to +7.5° with 1.5° increments to acquire 11 angular projections using 40 kVp, 500 μA with 5.55 s per projection. In continuous motion mode, the motorized stage moved the test object for the whole exposure time at a speed of 0.377 mm/s. The impact of acquisition speed in continuous DBT was also investigated, and a high speed of 0.753 mm/s was used. In step-and-shoot mode, the cutoff frequencies (10% MTF) in projection view (0°) and reconstructed DBT slices were 5.55 lp/mm and 4.95 lp/mm. Spatial resolution dropped in the continuous motion mode of the DBT due to the blur caused by the rotation of the stage and the cutoff frequencies reduced to 3.6 lp/mm and 3.18 lp/mm in the projection view (0°) and reconstructed DBT slices. At high rotational speed in continuous motion mode, the cutoff frequencies in the DBT slices dropped by 17 % to 2.65 lp/mm. Rotational speed of the rotation stage and spatial resolution are interconnected. Hence, reducing the motion blur in the continuous acquisition mode is important to maintain high spatial resolution for diagnostic purposes.

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Quantitative comparison of spatial resolution in step-and-shoot and continuous motion digital breast tomosynthesis

Abstract

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Keywords

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