Quantifying cortical atrophy

Eric Turkheimer, C. Munro Cullum, Donn W. Hubler, Sydney W. Paver, Ronald A. Yeo, Erin D. Bigler

Research output: Contribution to journalArticlepeer-review

38 Scopus citations


Most of the methods of quantifying cortical atrophy that have been proposed involve the estimation of the volume of enlarged sulci in the cerebral cortex. The authors propose that the surface area of the sulci is a more valid measure of cortical atrophy, and describe a system for measuring the surface area of the cortex, and present data in support of the method's reliability and validity.

Original languageEnglish (US)
Pages (from-to)1314-1318
Number of pages5
JournalJournal of Neurology, Neurosurgery and psychiatry
Issue number12
StatePublished - 1984

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology
  • Psychiatry and Mental health


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