Progression of leukoplakia of the bladder to squamous cell carcinoma 19 years after complete urinary diversion

Claus Roehrborn; C. M. Teigland; H. M. Spence

doi:10.1016/S0022-5347(17)41733-2

Progression of leukoplakia of the bladder to squamous cell carcinoma 19 years after complete urinary diversion

Claus Roehrborn, C. M. Teigland, H. M. Spence

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Abstract

We report a rare case of squamous cell carcinoma developing in a defunctionalized bladder with known leukoplakia 19 years after urinary diversion. We conclude from this case that once the initial metaplasia of the transitional epithelium of the urinary tract to leukoplakia has occurred chronic irritation by (infected) urine is not required to cause further progression to squamous cell carcinoma. Therefore, we recommend prophylactic cystectomy if palliative urinary diversion for relief of symptoms is considered in patients with leukoplakia of the bladder.

Original language	English (US)
Pages (from-to)	603-604
Number of pages	2
Journal	Journal of Urology
Volume	140
Issue number	3
DOIs	https://doi.org/10.1016/S0022-5347(17)41733-2
State	Published - 1988

ASJC Scopus subject areas

Urology

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10.1016/S0022-5347(17)41733-2

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title = "Progression of leukoplakia of the bladder to squamous cell carcinoma 19 years after complete urinary diversion",

abstract = "We report a rare case of squamous cell carcinoma developing in a defunctionalized bladder with known leukoplakia 19 years after urinary diversion. We conclude from this case that once the initial metaplasia of the transitional epithelium of the urinary tract to leukoplakia has occurred chronic irritation by (infected) urine is not required to cause further progression to squamous cell carcinoma. Therefore, we recommend prophylactic cystectomy if palliative urinary diversion for relief of symptoms is considered in patients with leukoplakia of the bladder.",

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AU - Roehrborn, Claus

AU - Teigland, C. M.

AU - Spence, H. M.

PY - 1988

Y1 - 1988

N2 - We report a rare case of squamous cell carcinoma developing in a defunctionalized bladder with known leukoplakia 19 years after urinary diversion. We conclude from this case that once the initial metaplasia of the transitional epithelium of the urinary tract to leukoplakia has occurred chronic irritation by (infected) urine is not required to cause further progression to squamous cell carcinoma. Therefore, we recommend prophylactic cystectomy if palliative urinary diversion for relief of symptoms is considered in patients with leukoplakia of the bladder.

AB - We report a rare case of squamous cell carcinoma developing in a defunctionalized bladder with known leukoplakia 19 years after urinary diversion. We conclude from this case that once the initial metaplasia of the transitional epithelium of the urinary tract to leukoplakia has occurred chronic irritation by (infected) urine is not required to cause further progression to squamous cell carcinoma. Therefore, we recommend prophylactic cystectomy if palliative urinary diversion for relief of symptoms is considered in patients with leukoplakia of the bladder.

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Progression of leukoplakia of the bladder to squamous cell carcinoma 19 years after complete urinary diversion

Abstract

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